摘要
目的 评估茵陈蒿汤和S 腺苷蛋氨酸两种药物治疗妊娠期肝内胆汁淤积症 (ICP)及改善围生儿预后的疗效。方法 将 6 0例ICP住院患者随机分为 2组 :A组采用茵陈蒿汤治疗 ,B组采用S 腺苷蛋氨酸治疗。治疗 3周后观察瘙痒症状 ,血清生化指标 (甘胆酸、胆红素、转氨酶 ) ,分娩后比较两组围生儿预后情况。结果 两组治疗后瘙痒症状、血清甘胆酸、胆红素、转氨酶均较治疗前明显改善 (P <0 0 5 ) ,但治疗后两组间围生儿预后差异无显著性 (P >0 0 5 )。结论 茵陈蒿汤与S 腺苷蛋氨酸均能有效治疗ICP ,前者价廉 ,适宜推广。
Objective To evaluate the therapeutic effect of Yinchenghao decoction (YCHD) and S-adenosy-L-methionine (SAM) in treating intrahepatic cholestasis of pregnancy (ICP) and improving prognosis of perinatal newborn babies. Methods Sixty in-patients of ICP were randomly divided into two groups,the group A treated with YCHD and the group B treated with SAM. The symptom of itching and serum biochemical indexes,including glycocholic acid,bilirubin and transaminase,were observed after 3 weeks treatment,and the prognosis of perinatal newborn babies between the two groups was compared after delivery. Results After treatment,the symptom of itching,serum levels of glycocholic acid,bilirubin and transaminase improved significantly (P<0.05) in both groups,and the prognosis of newborn in the two groups was similar (P>0.05). Conclusion Both YCHD and SAM could effectively treat ICP. The former is rather cheaper,so it is more feasible for spreading.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2004年第4期309-311,共3页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
妊娠期肝内胆汁淤积症
茵陈蒿汤
S-腺苷蛋氨酸
围生儿
预后
intrahepatic cholestasis in pregnancy
Yinchenghao decoction
S-adenosy-L-methionine
prognosis of perinatal newborn babies
blood-gas analysis of umbilical arterial blood
