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HGF和TGF-β_1在原发性肝癌根治性切除术后复发转移的作用

The Role of HGF and TGF - pi in Recurrence and Metastasis of Primary Liver Cancer after Radical Resection
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摘要 原发性肝癌是我国最常见的恶性肿瘤之一,外科切除是目前治疗的最重要手段,但术后高复发转移率是影响疗效进一步提高的关键障碍.在关于肝癌复发转移的研究中,原发性肝癌根治术后某些生长因子水平的变化是当前研究的新热点.
作者 王文清(综述) 邱双健 吴志全(审校)
机构地区 福建医科大学附属二院普外科 复旦大学肝癌研究所
出处 《中国临床医学》 2004年第2期260-261,共2页 Chinese Journal of Clinical Medicine
关键词 HGF TGF-β1 原发性肝癌 根治性切除术 复发 肿瘤转移 转化生长因子β1 肝细胞生长因子
分类号 R735.7 [医药卫生—肿瘤] R730.56 [医药卫生—肿瘤]
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参考文献17

  • 1NaKanishi K,Fujimoto J,Ueki T,et al. Hepatocyte growth factor promotes migration of human hepatocellular carcinoma via phosphatidylinositol 3 - Kinase. Clin Exp Metastasis, 1999, 17:507-514.
  • 2He J, Li Q, Zaide W, et al. Increased ievei of serum hepatocyte growth factor/scatter factor in liver cancer is associated with tumor metastasis. In Vivo, 1999,13:177- 180.
  • 3Kamiyama T, Une Y,Uchino J, et al. Hepatocyte growth factor enhances the invasion activity of human hepatocellular carcinoma cell lines. Int J Oncol, 1998,12: 655 -659.
  • 4Junbo H,Li Q, Zaide W,et al. Increased level of serum HGF(HSF) in liver cancer is associated with tumor metastasis. In Vivo, 1999,13(2): 177-180.
  • 5Michalopoulos GK, DeFrances MC. Liver regeneration. Science, 1997,276: 60-66.
  • 6Hu RH,Lee PH,Yu SC,et al. Serum hepatocyte growth factor before and after resection for hepatocellular carcinoma. Hepatogastroenterology, 1999, 46:1842- 1847.
  • 7Picardo A,Karpoff HM, Ng B, et al. Partial hepatectomy accelerates local tumor growth potential roles of local cytocike activation. Surgery, 1998, 124:57-64.
  • 8Ito N,Kawata SS,Tamurs S,et al. Expression of transforming growth factor- beta1 mRNA in human hepatocellular carcinoma. Jpn J Carcer Res, 1990,80:1202- 1205.
  • 9Yuen MF, Hughes RD, Heneghan MA, et al. Expression of Fas antigen (cd95) in peripheral blood lymphocytes and in liver - infiltrating, cytotoxic lymphocytes in patients with hepatocellular carcinoma. Cancer, 2001, 92: 2135～2141.
  • 10Bedossa P,Terris B,Franco D, et al. Transforming growth factor -beta1 receptor in normal, cirrhotic and neoplastic human livers. Hepatology,1995, 21:760.

二级参考文献12

  • 111，Kim KW,Bae SK,Lee OH,et al. Insulin-like growth factor Ⅱ induced by hypoxia maycontribute to angiogenesis of human hepatocellular Carcinoma. Cancer Res,1998,58(2):348～351.
  • 212，El Assal ON,Yamanoi A,Soda Y,et al. Clinical significance of microvessel density andvascular endothelial growth factor expression in hepatocellular carcinoma and surroundingliver:possible involvement of vascular endothelial growth factor in the angiogenesis ofcirrhotic liver. Hepatlogy,1998,27(6):1554～1558. (
  • 31，Regimbeau JM,Olivier F,Bai YS,et al. Is surgery for largehepatocellular carcinoma Justified. J Hepatol,1999,31(2):1062～1068.
  • 42，Neaud V,Faouzi S,Guirouilh J,et al. Human hepatic myofibroblasts increase invasivenessof hepatocellular carcinoma cells:eidence for a role of hepatocyte growth factor.Hepatology,1997,26(6):1458～1463.
  • 53，Picardo A,Howard M,Karpoff,et al. Partial hepatectomy accelerates local tumorgrowth:potential roles of local cytokine activation. Surgery,1998,124(1):57～64.
  • 64，Santoni RE,Jenson MR,Thorgeirsson SS,et al. Disruption of the pRb/E2F pathway andinhibition of apoptosis are major oncogenic events in liver constitutively expresing c-mycand transforming growth factor alpha. Cancer Res,1998,58(1):123～130.
  • 75，Tsai JF,Jeng JE,Chuang LY,et al. Elevated urinary transforming growth facyor-beta 1 asa tumor marker and predictor of poor survival in cirrhotic hepatocellular carcinoma.Cancer,1997,76(2):244～254.
  • 86，Pardoux C,Paturel CA,Chehimi J,et al. Functional interaction between TGF-β and IL-12in human primary allogeneic cytoxicity and proliferative response. JImmunol,1997,158(1):136～143.
  • 97，Gressner AM,Lahme B,Mannherz HG,et al. TGF-beta-mediated hepatocellular apoptosis byrat and human hepatoma cells and primary rat hepatocytes. J Hepatol,1997,26(5):1079～1083.
  • 108，Choi KS,Lim IK,Brady JN,et al. ICE-like protease(caspase)is involved in transforminggrowth factor beta l-mediated apoptosis in FaO rat hepatoma cell line.Hepatology,1998,27(2):415～422.

共引文献38

中国临床医学
2004年 第2期

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