摘要
目的:探讨影响甲状腺髓样癌(MTC)预后的因素。方法:回顾性分析73例MTC手术治疗、术后放疗的临床和随访资料。结果:73例MTC中37例发生于30-40岁,女性多发,临床Ⅱ,Ⅲ期病例占到83.6%;根据有无颈部淋巴结肿大行癌灶局部广泛切除或甲状腺癌联合根治术,切除不满意者辅以术后放疗。治疗后Ⅰ期病例五年生存率达100％,Ⅲ期为41.5%,Ⅳ期为零。8例姑息性切除辅以放疗者无1例生存达到5年。结论:临床分期和癌灶及其转移淋巴结切除的彻底性是影响MTC预后的重要因素。肿物巨大而累及较广泛者,因有不完整的包膜而常能被完全切除,即使有少量癌灶残留,术后辅以放疗,也可取得较好的疗效,而不应轻易放弃手术治疗。
Purpose: To explore the prognostic factors of medullary thyroid carcinoma( MTC) . Methods: The current study was designed to collect and analyze the clinical and follow-up information of 73 cases of MTC treated in our hospital. Results: It was shown that 37 cases were patients aged 30-40 years, it was more common in female than male, 83. 6% of these cases were regarded as clinical stage Ⅰ toⅢ. After treatment, the survival rate for 5 years were 100% , 41. 5% and 0 in the group of clinical stage Ⅰ,Ⅲ and IV respectively. None of those 8 cases in which the masses were incompletely removed surgically combined with the postoperative radiotherapy survived up to 5 years. Conclusions: The clinical stage, the thoroughness of the remove of MTC and its metastasis were the significant prognostic factors in our patients. It should be recognized that in most cases of MTC, though the mass was huge, it could be removal completely because it has an incomplete capsule. Although a little cancerous tissue might be left after operation, the prognosis is good after the postoperative radiotherapy. Therefore attempts of surgical removal of the cancerous mass should not be given up easily.
出处
《中国癌症杂志》
CAS
CSCD
2004年第2期167-169,共3页
China Oncology
关键词
甲状腺髓样癌
诊断
治疗
预后
medullary thyroid carcinoma
diagnosis
treatment
prognosis
