摘要
40日令SD品系大鼠长期喂养氚水。实验结果证明:大鼠的寿命随饮水中氚水放射性强度的增加显著缩短。高剂量组肿瘤发生率显著增加(73.3％),其中恶性肿瘤占肿瘤总数的77％。低剂量组肿瘤发生率也显著增加(79.3％),其中恶性肿瘤占肿瘤总数的79％。两个剂量组恶性肿瘤的比例是78％。可见氚水有显著地诱发肿瘤和致癌效应。本文中根据肿瘤的总数统计了氚水诱发肿瘤的危险度。
Sprague-Dawley rats of forty days old drank tritiated water (HTO) to end dead. The result showed that the life of rats significant decreased with doses increase. The incidence rate of tumor is increased significantly (73.3%) in rats of high dose group. Among others, the malignant tumors were 77% in the total of tumors. The incidence rate of tumor is increased significantly (79.3%) in rats of low dose group. Among others, the malignant tumors were 79% in the total of tumors. The incidence rate of malignant tumors were 78% for two doses groups.It have been confirmed that HTO clearly induced tumor and carcinogenic effect.The risk of HTO induced tumor was estimated on the basis of total tumors in the paper.
出处
《癌变·畸变·突变》
CAS
CSCD
1992年第3期1-4,共4页
Carcinogenesis,Teratogenesis & Mutagenesis
