摘要
报告1例以广泛皮肤栓塞坏死为突出表现的原发性抗磷脂抗体综合征。患者女,45岁。在1个月内发生双上臂伸侧、双肋胁部及两侧腹部下方多处皮肤梗死,同时伴有脾内多发性栓塞、不完全性肠梗阻及自身免疫性血小板减少(ITP),实验室检查显示狼疮抗凝物质(LA)中至强阳性。开始以大剂量皮质类固醇及大剂量丙种球蛋白静脉注射治疗ITP,进一步抗凝治疗取得一定疗效。
A case of primary antiphospholipid syndrome with extensive cutaneous necrosis was reported. A 45 year-old female presented with cutaneous infarct on her exterior lateral of the both upper arms, the costal region and inferior side of the flank within only one month, which was accompanied by spleen embolism, incomplete ileus as well as autoimmune thrombocytopenia. There was a medium to strong positive lupus anticoagulant(LA). At first, high dose corticosteroid and intravenous immunoglobulin were used to treat thrombocytopenia, and then anticoagulation was added to improve the situation.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2003年第7期399-400,共2页
Journal of Clinical Dermatology
