摘要
对34例智力低下患者的大脑皮质进行了病理组织学研究,其中8例进行了超微结构观察。结果表明,本组病例的主要病理改变为大脑皮质结构异常,如神经细胞排列紊乱及变性、固缩和脱失,伴胶质细胞增生、神经原纤维与髓鞘病变等。由此认为,智力低下可能与大脑皮质的原发性和(或)继发性损害有密切关系。
In this research, histopathology of the cerebral cortex was studied in 34 eases of mental retardation, and ultrastucture of the cerebral cortex was observed in 8 cases of them. The main pathological changes of the cerebral cortex in these patients inelude: the abnormalities of the cortical architecture; the irregular arrangement, degeneration, shrinkage and loss of neurons; and the lesions of neurofibrils and myelin, etc. From the above-mentioned, we consider that the pathogensis of mental retardation may be closely related to the primary and/or seeondary damages of the cerebral cortex. The correlations Of the pathological changes of the cerebral cortex with etiology and some symptoms were analysed in this paper.
出处
《临床神经病学杂志》
CAS
1992年第3期137-139,190,共3页
Journal of Clinical Neurology
