摘要
目的:探讨氯氮平所致类感染综合征的相关因素及处理方法。方法:由临床医师记录单用与联用氯氮平患者年龄、性别、病程、药物剂量及对类感染综合征的处理办法,临床药师汇总分析。结果:符合条件817例患者,出现类感染综合征122例(占14.9％),其中,发热106例,肺炎31例,白细胞增高27例,类感染综合征发生率与年龄呈正相关,与病程呈负相关,与性别、剂量无相关性。结论:老年及首次发病患者应慎用氯氮平,对于应用氯氮平无特别不适类感染综合征患者可不作特别处理,严重患者可选择停药。
OBJECTIVE: To study correlative factors of analogous infection syndrom caused by Leoponex and treating method . METHODS: To record the age, sex, course of disease, drug dosage of the patients who single and combined using Leoponex and treating method for analogous infection syndrom. These materials were analyzed by clinical pharmacists. RESULTS: 817 cases were chosen. 122 cases occurred analogous infection syndrom (14.9%), of those, 106 cases had fever 31 suffered from pneumonia,27 had leucocytosis; the incidence of analogous infection syndrom was positively correlative to the age , negatively correlative to course of disease and there was no correlation to sex and dosage. CONCLUSION: It must be carefully used by aged patients and the patients occurring the disease first time. If the patients have no uncomfortable feeling when using Leoponex, there is no need for special treatment, but severe patients should stop using this drug.
出处
《中国医院用药评价与分析》
2004年第1期45-47,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
