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基因治疗临床应用的研究进展 被引量:2

Gene Therapy and Its Advance on Clinic Applications
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摘要 基因治疗作为一种新型的疾病治疗手段,正在广泛用于多种疾病的治疗领域.简单介绍了基因治疗的基本途径和临床应用. Gene therapy is a method that can cure disease through introducing foreign gene to the body.It is a new biology technique and widely used for treating many diseases.The status gene therapy including the basic methods,gene expression and its clinic application was presented in this article.
出处 《河北师范大学学报(自然科学版)》 CAS 2004年第3期298-302,共5页 Journal of Hebei Normal University:Natural Science
关键词 基因治疗 基因表达 基因药物 目的基因转移 可诱导表达系统 遗传性疾病 gene therapy gene expression clinic application
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参考文献18

  • 1BLAESE R M.T lymphocyte-directed gene therapy for ADA/SCID:Initial trial result after 4 years [J].Science,1995,270:270-275.
  • 2DURING M J,XU R,YOUNG D,et al.Peroral gene therapy of lactose intolerance using an adeno-associated virus vector [J].Nat Med,1998,(4):1131-1135.
  • 3ZHENG C,BAUM B J,IADAROLA M J,et al.Genomic integration and gene expression by amodified adenoviral vector [J].Nature Biotechnol,2000,18:176.
  • 4STABA M J,MAUCERI H J,KUFE D W,et al.Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignantglioma xenograft [J].Gene Ther,1998,(5):293-300.
  • 5RINSCH C,REGULIER E,DEGLON N,et al.A gene ther approach to regulated delivery of erythropoietin as a function of oxygen tension [J].Hum Gene Ther,1997,8(16):1881-1889.
  • 6BURCIN M M,SCHIEDNER G,KOCHANEK S,et al.Adenovirus-mediated regulable target gene expression in vivo [J].Proc Natl Acad Sci USA,1999,96:355-360.
  • 7NIEDERMAN T M,GHOGAWALA Z,CARTER B S,et al.Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors [J].Proc Natl Acad Sci USA,2002,99(10):7009-7014.
  • 8MOON W C.Clinical study on intraarterial p53 gene therapy for liver cancer [J].Chung Ang University,1999,16(3):43-46.
  • 9NISHIZAKI M,FUJIWARA T,TANIDA T,et al.Recombinant adenovirus expression wild-typy p53 is antiangiogenic:A proposed mechanism for bystander effect [J].Clin Cancer Res,1999,5(5):1015-1023.
  • 10SEKI M,IWAKAWA J,CHENG H,et al.p53 and PTEN/MMACI/TEP1 gene therapy of human prostate PC-3 carcinoma xenograft,using transferrin-facilitated lipofection gene delivery strategy [J].Hum Gene Thec,2002,13(6):761-773.

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