摘要
对50名无明显阻力性难产,而因子宫收缩乏力引起产程延缓,用催产素进行治疗初产妇所用的催产素滴度、子宫收缩力水平变化及血和羊水中雌、孕激素水平之间关系进行分析。结果表明:(1)应用催产素前的子宫收缩力分别为334±188KPaS/15min,或89±52MU/15min;应用催产素后分别为1201±241KPaS/15min,或308±68MU/15min,后者明显高于前者,有显著性差异(P<0.001)。(2)有效催产素滴度范围是:2—6mU/min,但74％≤10mU/min。(3)产力难产组羊水中雌二醇水平与催产素滴度间相关系数γ=-0.4120,P<0.05。此结果提示子宫对催产素的敏感性与羊水中雌激素水平有关。
Uterine activity and uterine reaction to oxtocin were studied in 50 women who progressing slowly in spontaneous labour. The results are:(1) The mean level of uterine activity was 334±188KPas/15min? or 89±52MU/15min before oxytocin augmentation. Following oxytocin infusion,there was a signi ficant increase in uterine activity to a mean of 1201±241KPas/15min,or 308±68MU/min,which were the same as in normal spontaneous labour. (2) The rate of oxytocin infusion varied between patients from 2 to 60mU/min but in 74%uterine activity was corrected to normal levels by a dose of ≤10mU/min. (3)The level of estradiol in aminiotic fluid is related to the rate of oxytocin infusion (r=-0. 4120,P<0.05). This finding suggest that uterine response and sensitivity to oxytocin may be associated with the level of estradiol in aminioticfouid.
出处
《合肥医学院学报》
1992年第3期13-17,共5页
Journal of Zunyi Medical University
