摘要
本文动态视察45例急性格林—巴利综合征(GBS)血皮质醇浓度比正常组显著增高(P<0.05);其增高浓度与病情有关,死亡组>极重型>重型>中轻型;病情进展期皮质醇浓度高而淋转率低,随病情好转皮质醇浓度下降,淋转率升高。认为该病皮质醇升高与神经内分泌免疫调节有关,高含量皮质醇不利于抗原清除和髓鞘再生,血皮质醇测定对病情预后判断有参考价值。
This paper determined dyna-mically 45 cases of GBS and theserum cortisol concentration is obv-iously higher than the normal gro-up(P<0.05).The raising concen-tration is Hlated to the seriousnessof the disease.The dead group>the very serious group>the seriousgroup>the minimal medium group.In the grogressive stage of the di-sease the cortisol is high and therate of the lymphtic metastasis islow.As the biseasegets 6etter thecortisol decreases and the rate ofthe lymphtic metastasis increases. It is believed that the increase ofthe cortisol of this disease relatesto the immunoregulation of thenervous endocrine.the high conte-nted cortisol is disadvantageous tothe antigen cleaning and myelinsheath regeneration.The determination of serum cortisol is quitevaluable for the progrosisof the disease.