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Albendazole versus metronidazole treatment of adult giardiasis:An open randomized clinical study 被引量:2

Albendazole versus metronidazole treatment of adult giardiasis:An open randomized clinical study
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摘要 AIM:To investigate the efficacy and tolerability of albendazole and metranidazole treatment in giardiasis. METHODS:The open comparative randomized trial was carried out prospectively from December 1999 to July 2001 in Duzce City of Turkey.The diagnosis was based on the presence of signs and symptoms compatible with giardiasis including a positive stool examination of giardia cysts or trophozoite.Metranidazole group consisted of 29 patients and was given metranidazole 500 mg,three times a day for 5 d and albendazole group was consisted of 28 patients and was given albendazole 400 mg/d for 5 d. RESULTS:There were no significant differences in demographical and therapeutical effects and patient's compliance between both groups.But side effects were seen more in metranidazole group than in albendazole group. CONCLUSION:Albendazole is as effective as metranidazole in adults' giardiasis.Albendazole has less side effect potentials than metranidazole in the treatment of giardiasis. To investigate the efficacy and tolerability of albendazoleand metranidazole treatment in giardiasis.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第8期1215-1217,共3页 世界胃肠病学杂志(英文版)
关键词 ADULT ALBENDAZOLE DOSAGE Antiprotozoal Agents Antitrichomonal Agents Comparative Study Female GIARDIASIS Humans Male METRONIDAZOLE Middle Aged Prospective Studies Treatment Outcome 丙硫咪唑 甲硝哒唑 梨形鞭毛虫病 药物疗法 成人 随机临床研究 耐受性
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