摘要
目的 观察鼾症对冠心病病人的影响。方法 5 2例病人分为两组 ,2 6例鼾症合并冠心病病人(A组 ,鼾症组 )与 2 6例非鼾症冠心病病人 (B组 ,非鼾症组 )进行观察 ,比较两组间血压昼夜节律 ,夜间平均血氧饱和度及夜间最低血氧饱和度、心肌缺血次数等指标。同时比较鼾症组部分病人经鼻持续气道正压通气(nCPAP)治疗前后各项指标。结果 鼾症组中肥胖、高血压人数高于非鼾症组人数 ,冠心病发病年龄早于非鼾症组 ,易发生血压昼夜节律消失 ,夜间平均SaO2 及夜间最低SaO2 明显低于非鼾症组 ,鼾症组冠心病心肌缺血使用硝酸酯类扩冠药物疗效不佳 ,nCPAP有助于改善鼾症组病人病情。结论 鼾症与高血压、冠心病有密切的相关性 ,经鼻持续气道正压通气治疗冠心病合并鼾症有效。
Objective To investigate the effect of snore on the patients with coronary heart disease.Methods Fifty two patients with coronary heart disease were divided into snore group(group A,26 cases) and non snore group(group B,26 cases).The continuous Holter EKG,blood pressure,SaO 2 measurement,the day to night rhythm of BP,the average SaO 2 at night,the lowest SaO 2 at night,the times of myocardial ischemia were compared between the two groups as well as before and after nasal continuous positive airway pressure(nCPAP) treatment for 5～7 days in snore group.Results The number of patients with fat and hypertension in group A were higher than those in group B,the average age of the occurrence of coronary heart disease was younger in snore group.The incidence of disappearance of day to night rhythm of BP was significantly higher and the incidences of average SaO 2 and the lowest SaO 2 at night were obviously lower in group A than those in group B.Poor effectiveness of nitrate on myocardial ischemia was found in group A.nCPAP was benefit to snorners.Conclusion There is a close association between snore and hypertension,coronary heart disease.nCPAP is effective on snorners with coronary heart disease.
出处
《中国基层医药》
CAS
2004年第3期286-287,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
冠心病
合并症
鼾症
硝酸酯类药物
治疗
Snore Coronary heart disease Mean artery pressure(MAP) SaO 2 Nasal continuous positive airway pressure(nCPAP)
