摘要
目的 探讨同种异体气管移植再血管化与再上皮细胞化的研究进展。 方法 广泛查阅近期相关文献 ,介绍一种先将同种异体移植段气管大网膜包裹 ,血管化后再种植自体上皮细胞后原位移植的方法。 结果 与一期原位移植加大网膜包裹相比 ,增加上皮细胞覆盖率 ,使之最接近自体生理条件。 结论 这一方法若能成功 ,可进一步减少移植段气管免疫排斥反应 ,防止其塌陷 ,延长患者生存时间。
Objective To study the research advance in tracheal allografts undergoing revascularization and reepithelialization. Methods The recent literature concerned was reviewed. The tracheal allografts are embedded in the omentum, which they were revascularized and reepithelialized by planting in self-epithelia, then the allografts with their omental pedicles were transplanted orthotopically to the cervical or the thoracic portion of the trachea. Results Compared with the one-stage tracheal allograft approach using the greater omentum, the two-stage approach could increase the successful rate of revascularization and reepithelialization, and made the allografts accord with their physiology. Conclusion If the approach is successful, it can reduce graft-rejection, prevent graft-collapse and increase graft-viability after tracheal allograft.
出处
《中国修复重建外科杂志》
CAS
CSCD
2004年第3期236-238,共3页
Chinese Journal of Reparative and Reconstructive Surgery
