摘要
目的:观察C反应蛋白(CRP)在不稳定性心绞痛(UA)危险度分层中的作用。方法:在UA 86例、稳定性心绞痛(SA)49例,正常对照组36例测定CRP浓度,按照《建议》的分层将86例UA患者分为低、中、高危险组,比较各级的CRP浓度,观察恶性室性心律失常、心脏病事件的发生率。结果:UA组CRP水平高于对照组、SA组(P<0.05)。低、中、高危险组的CRP浓度分别是(11.23±0.79)mg/L、(13.78±0.82)mg/L及(16.85±0.87)mg/L,两两比较有显著性差异(P<0.05),恶性室性心律失常、心脏病事件的发生率递增(P<0.05-<0.01)。结论:随着UA危险度分层的增加,CRP浓度依次增加。(CRP水平是UA患者危险度分层的重要指标。
Objective: To study the effects of plasma C-reactive protein (CRP) on risk classification of unstable angina ( UA). Methods: The plasma CRP levels in 86 cases with UA, 49 cases with stable angina (SA) and 36 controls were measured. According to 'Guide'classification, the patients with UA were divided into low grade, middle grade and grade. The malignant ventricular arrhythmia. cardiovascular events were observed in these three groups. Results: The plasma CRP levels increased in patients with UA compared with those in patients with SA and the control group (P <0. 05). The plasma CRP levels in three groups of UA were (11. 23±0. 79)mg/L, (13. 78±0. 82)mg/L and (16. 85±0. 87) mg/L respectively. There was significant variety between each other (P<0. 05). The malignant ventricular arrhythmia and cardiovascular events increased progressively in these three groups (P<0. 05-<0. 01). Conclusion: CRP increase as the increasing of risk grade. The plasma CRP levels can be seen as an index for the risk classification of UA.
出处
《心血管康复医学杂志》
CAS
2004年第2期121-123,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine