摘要
目的探讨低分子肝素皮下注射时轮换注射部位与皮下出血发生率及出血面积的关系。找出有效的轮换注射部位的方法 ,以减少皮下出血的发生率及面积。方法选择急性心肌梗死和不稳定心绞痛病人 4 0例 ,将其分为实验组和对照组各 2 0例。实验组皮下注射低分子肝素时有规律地轮换注射部位 ,对照组随机轮换注射部位 ,两组各注射 2 4 0例次 ,观察两组皮下出血发生率及出血面积。结果实验组皮下出血发生率显著低于对照组 (P <0 .0 1) ,出血面积显著小于对照组 (P <0 .0 5 )。结论有规律地轮换注射部位可以减少皮下出血发生率及出血面积。
Objective To investigate the correlation between regularly changing subcutaneous injection location of low molecular-weight heparin and the incidence and size of subcutaneous hemorrhage, and to find out the effective way to reduce incidence and area of subcutaneous hemorrhage. Methods Forty patients with acute myocardial infarction (AMI) or unstable angina pectoris were randomly divided into experimental group (n=20) and control group (n=20). In the experimental group, low molecular-weight subcutaneous injection was given by regularly changing location, while in the control group, low molecular-weight subcutaneous injection was given by randomly changing location. Each group received 240 low molecular-weight injections. The incidence and size of subcutaneous hemorrhage was observed. Results The incidence and size of subcutaneous hemorrhage in the experimental group was significantly less than in the control group (P<0.05,P<0.01). Conclusion Regularly changing subcutaneous injection location of low molecular-weight heparin can reduce the incidence and area of subcutaneous hemorrhage.
关键词
肝素
低分子量
注射
皮下
出血
heparin, low molecular-weight
injection, subcutaneous
hemorrhage