摘要
目的 了解临床分离的耐甲氧西林的金黄色葡萄球菌(MRSA)对医院常用消得剂的抗性。方法 测定碘伏和氯已定对MRSA、甲氧西林敏感的金黄色葡萄球菌(MSSA)和金鱼色葡萄球菌ATCC6538的最小抑菌浓度(MIC)。结果 碘伏对MRSA的MIC明显高于MSSA,在38株MRSA中5.3％菌株的MIC是质控菌株的2倍,28.95％菌株的MIC为质控菌株的1.5倍,而18株MSSA中仅有11.1％菌株的MIC是质控菌株的1.5倍,83.3％菌株的MIC值与质控菌株相同。醋酸氯已定对MRSA、MSSA和金黄色葡萄球菌ATCC6538的MIC值相同。结论 部分MRSA菌株对碘伏抗性增高,MRSA对氯已定的抗性无明显增强。
Objective To study the resistance of methicillin--resistant staphylococcus aureus
(MRSA),an indicator used in hospitals. Methods We used minimal inhibitory concentrations(MIC) of
iodoph and chlorhexidine to MRSA, methicillin--sensitive staphylococcus aureus (MSSA) and
staphylococcus aures ATCC6538. Results Obvious difference between MRSA and MSSA the MIC of
lodophor was noticed. Among MICs, 5. 3 % MRSA strains were 2--folds and 28. 9 % MRSA strains were
1. 5 fold more than staph. aures ATCC6538, while the MIC of 11. 1 % MSSA strains raised 1. 5 fold than
ATCC6538. The MIC of 83. 3 % MSSA strains were the same to staph. aureus ATCC6538. The MIC of
chlorhexidine to MRSA, MSSA and staphyloccus aureus ATTC6538 were similar to each other.
Conclusion Results showed that some MRSA were more resistant to Iodophor than staph. aureus
ATCC6538, but remained the same resistance to Chlorhexidine. Thus the concentrationn of Iodophor should
be raised when the resistant strains were isolated.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2004年第3期248-250,共3页
Chinese Journal of Epidemiology
基金
江苏省应用基础基金(BJ1998030)
关键词
甲氧西林金黄色葡萄球菌
碘伏
氯已定
抗性
浓度
消毒剂
Methicillin-resistant staphylococcus aureus
Iodophor
Minimal ibhibitory concentration
