摘要
1980～1990年,作者收治原发性肝癌660例,手术切除124例(18.8％)。术后肝内复发者32例(肝内复发率25.8％),2 年以内复发者占93.8％。93.7％合并肝硬化,15.5％并发门脉高压症。复发肝癌中4例(3.2％,4/124)行再切除,术后生存平均26.8月;22例行B超引导肝癌复发灶无水酒精注射术,术后8例死亡,平均生存8.5月;10例行肝动脉栓塞化疗或肝动脉结扎及插管化疗,术后生存平均16.8月,对照组仅4.5月。复发癌再次外科治疗以再切除术为首选(术后生存26.8～42.6月),成为继小肝癌切除,大肝癌二期切除后提高肝癌切除疗效的第三条途径。
During the past 10 years the authers have treated 660 patients with primary hapato-cellular carcinoma (HCC). One hundred and twenty-four of them were treated by liver resection (18.8% ). Thirty-two of the patients with resectable HCCs have develop intrahe-patic metastases after operation. Twenty-eight men and four women average 42.5 years (range 9 to 65 years), 30(93.7%) with postnecrotic cirrhosis and 5(15.5%) with portal hypertension. For the patients with cancer recurrence, 3.2% (n=4) of them underwent the second resection. The mean survival time was 26.8 months after the second resection. Twenty-two of the patients had already been treated with injecting absolute ethanol directly into the tumor under ultrasound guidance. Eight patients died after the injecting. The mean survival time was 8.5 months. Ten of the patients had been treated with tran-scatheter hepatic arterial chemotherapy and embolization (TAEC-lipiodol, 5 Fu, MMC, ADR) and/or hepatic artery ligation and infusion chemotherapy. The mean survival time was 16.8 months. Control group only 4.5 months. It is concluded that repeat hepatecto-my for recurrent liver cancer as an important approach for improving the surgical result has been proved. Atypical resection are reasonable and acceptable for HCC, especial, for recurrent HCC. Ethanol injection therapy is a effective, palliative treatment for recurrent HCC, especial for the single nodule. TAEC/HAL + HAI provides an effective, palliative treatment for recurrent HCC. But TAEC did not improve the longterm survival time.
出处
《中山医科大学学报》
CSCD
1992年第4期64-67,共4页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
肝肿瘤
切除术
局部复发
liver neoplasms
hepatectomy
neoplasm recurrence
local
