摘要
应用悉尼胃炎新分类法对连续胃镜检查1006例进行前瞻性研究,结果:①除非溃疡性消化不良外,十二指肠溃疡、胃溃疡、复合性溃疡及胃癌的幽门螺杆菌(HP)检出率均显著高于当地同期人群(P<0.05)。上述胃、十二指肠疾病中,92.7％有组织学上表现的慢性胃炎,其中HP阳性占83.7％、HP阴性占16.3％。前者主要表现为慢性全胃炎一胃窦为主,且炎症明显并伴有活动性改变;后者为慢性胃窦炎,其炎症轻亦无活动性改变。②十二指肠溃疡、胃溃疡、胃癌三者间存在明显不同的慢性胃炎模式(慢性炎症分布、萎缩程度及范围大小)。结果表明,悉尼胃炎分类诊断项目全面具体,有利于资料积累和分析,对HP及其相关性疾病的研究有特别重要价值。
The 'Sydney System' for the classification of gastritis in 1 006 consecutive gastrosc-opy patients was applied. It was found that:(1)H. pylori (HP) incidences were as follows: duodenal ulcer (DU) 98.9%, combinded ulcer (CU) 100%, gastric ulcer (GU) 100%, gastric cancer (GC) 83.3% and non-ulcer dyspepsia (NUD) 57.4%. HP incidences in all but NUD groups were significantly higher than that in general population. Histological chronic gastritis was identified in 92.7% of all above patients, of which HP ( + ) gastritis, 83.7% and HP ( - ), 16.3%. Moderate and severe inflammation with activity and pangastritis-antral predominant were common in HP ( + ) group; whereas mild inflammation without activity and antral gastritis were common in HP ( - ) group. (2) The pattern of chronic gastritis was quite different in ^different gastric disorders. In GU and GC, pangastritis-uniform, moderate to severe atrophy (usually diffuse atrophy in both the antrum and the corpus) was more common; whereas in DU, pangastritis-antral predominant was more common and moderate to severe atrophy (atrophy located only in the antrum if it existed) was seldom; the pattern of chronic gastritis in NUD was similar to that seen in DU. The results indicate that Sydney System makes good assessment of gastritis simple and applicable in big sample size analysis, because it consists of comprehensive diagnostic parameters including aetiological (pathogenic)association, topography and grading of morphology. The introduction and application of this system would particularly promote the study of HP and its associated diseases.
出处
《中山医科大学学报》
CSCD
1992年第3期56-60,共5页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
胃炎
分类法
幽门螺杆菌
胃镜检
gastritis
classification
helicobacter pylori
duodenal ulcer
gastric ulcer
gastric cancer
