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心脏直视术后胸腔引流血中性白细胞凋亡与回输的影响

Apoptosis of WBC in thoracic drained blood after cardiac surgery and its effect on reinfusion
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摘要 目的 测定胸腔引流血中性粒细胞凋亡 ,以了解胸腔引流血回输对人体的影响。方法 随机选择心脏直视手术后 1 0名患者 ,分别于术后 4~ 6h采集胸腔引流血 1 0ml,同时取该病人动脉血 1 0m1 ,另取 1 0份库血 ,每份1 0ml,测定中性粒细胞DNALadder,AnnexinV和Capase 3。 结果 DNALadder测定显示胸腔引流血DNA含量比循环血高 ,但比库血低 ;AnnexinV测定显示胸腔引流血其值高于库血和循环血 ;Capase3活力测定显示胸腔引流血Capase3活力接近库血 ,明显高于循环血。 结论 胸腔引流血中性粒细胞凋亡增强 ,从而对肺部影响小于库血和循环血。
出处 《中国输血杂志》 CAS CSCD 2004年第2期103-104,共2页 Chinese Journal of Blood Transfusion
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  • 1StahlRF, Fisher CA, Kucich U, et al. Effects of stimulated extracorporeal circulation on human leukocyte elastase release, superoxide generation,and procoagulant activity. J Thorac Cardiovasc Surg,1991,191(2) :230
  • 2Gadaleta D, Fahey AL, Verma L, et al. Neutrophil leukotriene generation increases after cardiopulmonay bypass. J Thorac Cardiovasc Surg, 1994,108(4): 642
  • 3Riegel W,Spillner G,Schlosser V,et al. Plasma levels of main granulocyte, components during cardiopulmonary bypass. J Thorac Cardiovasc Surg, 1988,95(6): 1014
  • 4Anftonsen S, Brandslund I, Clemensen S, et al. Neutrophil lysosomal enzyme release and complement activation during cardiopulmonary bypass. Scand J Cardiovasc Surg,1987,21(1):47
  • 5Kongsgaard UE, Smith-Erichsen N,Geiran O,et al. Different activation patterns in the plasma kalliRrein-kinin and complement systems during coronary bypass Surgery. Acta Anaesthesiol Scand,1989,33(5) :343
  • 6Cox G,Crossley J,Zhou X. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation vivo. Am J Respir Cell Mol Bio, 1995,12(2): 232

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