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体外循环与非体外循环下冠状动脉搭桥术后炎性反应和心肌损伤的比较 被引量:4

Inflammatory response and myocardial injury after coronary artery bypass grafting with and without cardiopulmonary bypass
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摘要 目的 对比观察体外与非体外循环下冠状动脉搭桥术 (CABG)后炎性细胞因子和心肌损伤指标的变化情况。方法  35例CABG患者 ,分成常规体外循环下CABG(CABG组 ,15例 )和非体外循环下CABG(OPCAB组 ,2 0例 ) ,分别于麻醉诱导后和术后 0、2、6、12、2 4小时抽取桡动脉血样检测肿瘤坏死因子 α(TNF α)、白细胞介素 6 (IL 6 )、白细胞介素 8(IL 8)、可溶性细胞间黏附因子 1(sICAM 1)、心脏肌钙蛋白I(cTnI) ,并记录术后早期的各项临床指标。结果 术后IL 8、TNF α、cTnI在CABG组较OPCAB组明显升高 ,sICAM 1、IL 6在两组间无明显差异。结论 和常规CABG相比 ,非体外循环 (CPB)下的CABG可以减轻术后炎性反应和心肌损伤。
出处 《江苏医药》 CAS CSCD 北大核心 2004年第3期178-179,共2页 Jiangsu Medical Journal
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参考文献7

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同被引文献35

  • 1宋琳琳,王东信,吴新民,赵国立.体外循环与非体外循环下冠脉搭桥术病人围术期炎性反应和肺功能的比较[J].中华麻醉学杂志,2005,25(2):85-89. 被引量:9
  • 2张海涛,胡盛寿,孙寒松,刘楠,杨九光,龙村.体外和非体外循环冠脉搭桥术炎性介质的比较[J].中国体外循环杂志,2006,4(1):23-25. 被引量:13
  • 3魏民新,杨洁,李庆和,简锴陶,郭志鹏,Matti Tarkka.冠状动脉搭桥术后心脏炎症因子变化[J].天津医药,2006,34(8):516-518. 被引量:1
  • 4解丽君,张建新,李兰芳.异丙酚对离体大鼠心肌缺血/再灌注损伤的保护作用[J].中国药理学通报,2007,23(5):635-641. 被引量:14
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