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兔眼后房型人工晶状体植入术后循环免疫复合物动态观察

Dynamic observation of circulating immune complex after cataract extraction with the implantation of posterior chamber intraocular lens in rabbit eyes
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摘要 目的 研究后房型人工晶状体植入术后循环免疫复合物(CIC)的变化及人工晶状体对CIC的影响。方法 大耳白兔40只,随机分为A、B两组,每组20只;A组行右眼透明晶状体超声乳化吸出联合人工晶状体植入;B组行右眼透明晶状体超声乳化吸出。分别在术前及术后第7、14、21、28和35d采血,用聚乙二醇比浊法测定CIC。结果 A、B两组术后CIC均升高,于术后第21d达最高峰,35d降至术前水平,两组间差异无显著性(t=0.37 P>0.05)。结论兔眼后房型人工晶状体植入术后,CIC升高持续4~5周,人工晶状体植入与术后CIC变化无明显相关性。 Objective To study the changes of circulating immune complex ( CIC ) after cataract extraction with implantation of posterior chamber intraocular lens( PC-IOL) and to investigate the effects of the IOL on the CIC. Methods Fourty experimental rabbits were randomly divided into 2 equal groups. Phacoemulsification with PC-IOL was performed in group A but only phacoemulsification in group B. Before operation and the 7th, 14th,21st,28th and 35th days after the operation, CIC was detected with polyethylene glycol comparison method. Results CIC was markedly elevated after the surgery in both groups,and there was no significant difference between group A and group B(P>0. 05). Conclusions Level of CIC remains high for 4 - 5 weeks following the operation in rabbit eye. Polgmethglmethacrylate ( PMMA) IOL is not apparently related to CIC variation.
出处 《眼科研究》 CSCD 北大核心 2003年第4期371-373,共3页 Chinese Ophthalmic Research
关键词 兔眼 后房型人工晶状体植入术 循环免疫复合物 动态观察 rabbit eye cataract extraction intraocular lens circulating immune complex
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