4Smith DJ,Shoushtari B,HeSchel RL,et al.Immunogenicity and protective immunity induced by synthetic peptides associated with a catalytic subdomain of mutans group streptococcal glucosyltransferase[J].Infect Immun,1997,65(11):4424
5Smith DJ,Trantolo DJ,King WF,et al.Induction of secretory immunity with bioadhesive poly co,L-lactide-co-glycolide,Microparticles containing Streptoloccus Sobrinus glucosyltransferase[J].Oral Microbiol Immunol,2000,15(2):124
6Childers NK,Zhang SS,Harokopakis E,et al.Properties of practical oral liposome-Streptococcus mutans glucosyltransferase vaccines for effective induction of caries protection[J].Oral Microbiol Immunol,1996,11(3):172
8Hamada S,Horikoshi T,Minami T,et al.Oral Passive immunization against dental caries in rats by use of hen egg yolk antibodies specific for cell-associated glucosyltransferase of Streptococcus mutans[J].Infect Immun,1991,59(11):4161
9Radman YK,Harmon CC,Lallone RL,et al.Oral immunization with recombinant Salmonella typhimurium expressing surface protein antigen A of Streptococcus sobrinus:dose response and induction of protective humoral responses in rats[J].Imfect Immun,1995,63(5):20
10Redman TK,Harmon CC,Lallone RL,Michalek SM.Comparison of an adherence domain and a structural region of Streptococcus mutans antigen Ⅰ/Ⅱ in protective immunity against dental caries in rats after intranasal immunization[J].Infect Immun,1998,66(4):1740
二级参考文献25
1凌均--,华西口腔医学杂志,1995年,13卷,163页
2凌均--,口腔医学纵横,1995年,11卷,195页
3凌均--,华西口腔医学杂志,1994年,12卷,86页
4凌均--,口腔医学纵横,1993年,9卷,193页
5吴乃虎,基因工程原理,1989年
6Forester H, Hunter N, Knox KW.Characteristics of a high molecular weight extracellular protein of Streptococcus mutans.J Gen Microbiol, 1983,129:2779-2788.
7Okahashi N, Sassakawa C, Yoshikawa M, et al. Cloning of a surface protein antigengene from serotype c Streptococcus mutans. Mol Microbiol,1989,3:221-228.
8Brandy LJ, Cvitkovitch DG, Geric CM, et al. Delection of the central proline-richrepeat domain results in altered antigenicity and lack of surface expression of theStreptococcus mutans P1 adhesin molecule. Infect Immun, 1998,66:4274-4282.
9Matsushita K, Nisizawa T, Nagaoka S, et al. Identification of antigenic epitopes ina surface protein antigen of Streptococcus mutans in humans. Infect Immun, 1994,62:4034-4042.
10Klavinskis LS, Barnfield C, Gao L, et al. Intranasal immunization with plasmidDNA-Lipoid complexes elicits mucosal immunity in the female genital and rectal tracts. JImmunol,1999,162:254-262.
5SMITH D J, KING WF, GODISKA R. Passive transfer of immunoglob- ulin Y antibody to Streptococcus mutans glucan binding protein B can confer protection against experimental dental caries. Infect Immun, 2001,69(5) :3135-3142.
6KRtiGER C, PEARSON SK, KODAMA Y, et al. The effects of egg- derived antibodies to glucosyltransferases on dental caries in rats. Caries Res, 2004,38(1) :9-14.
7Ressell MW,Moldoveanu Z, White PL,et al. Secretory immunity in defense against cariogenic mutans treptococci Caries res. 1997,33(1) :4 -15.
8Otake S, Nishihara Y, Makimura M, et al. Protection of Rats against Dental Caries by passive Immunization with Hen - egg Yolk antibody(IgY) [ J]. J Den RES, 1991,70( 3 ) :162 - 166.
9Kohler B, Birkhed D, Oission S,et al. Acid production by human strains of streptoccus mutans and streptoccus sobrinus [J]. Caries res,1995,29(5) :402 -406.
10Lindquist B, Emilson CG. Dental location of streptoccus mutans and streptoccus sobrinus in human harboring both species [ J ].Caries res,1997,25(2) :146 -152.