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甲状旁腺激素测定对原发性甲状旁腺功能亢进症的诊断意义(附9例临床病理报告) 被引量:8

SIGNIFICANCE OF PARATHYROID HORMONE MEASUREMENT IN THE DIAGNOSIS OF PRIMARY HYPERPARATHYROIDISM
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摘要 对经手术和病理证实的9例原发性甲状旁腺功能亢进症(PHPT)患者,进行血钙和甲状旁腺激素(PTH)等测定,血钙为2.17~3.6mmol/L(正常值为2~2.6mmol/L),PTH为165.5~1266.7mmol/L(正常值为20~90ng/L)。血钙间歇性升高4例,持续性升高5例,PTH各为<500ng/L和>500ng/L。病程<2年和>2年者,PTH各为<300ng/L和>300ng/L。瘤重<2g者,PTH均<500ng/L,而>2g者大多>500ng/L。提示PTH与血钙、病程和瘤重有关。如将PTH和血钙结合分析,可提高PHPT的诊断率。 Serum calcium and parathyroid hormone (PTH) concentrations were determined in 9 cases with primary hyper-parathyroidism (PHPT) proved by surgery and pathology. The range of serum calcium concentrations was 2.17-3.6 mmol/L (normal range 2-2.6 mmol/L). The range of PTH was 165.5-1 266.7 ng/L (normal range 20-90 ng/L). Four cases with intermittently elevated serum calcium levels had increased PTH concentrations up to 500 ng/L, while five cases with serum calcium concentrations continuously increased had PTH levels raised to above 500 ng/L. Patients with the courses of the disease less than two years and greater than two years had PTH<300 ng/L and PTH>300 ng/L respectively. Tumours weighing less than 2 g had PTH<500 ng/L, and tumours weighing more than 2 g had PTH>500 ng/L. These findings indicate that PTH levels were associated with serum calcium concentrations, course of disease and weight of the tumours. So if we analyse PTH and serum calcium concentrations at the same time, we can improve the diagnosis of PHPT.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 1992年第3期135-136,共2页 Chinese Journal of Endocrinology and Metabolism
关键词 甲状旁腺激素 甲旁亢 诊断 Parathyroid hormone Hyperparathyroidism
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参考文献1

  • 1钟学礼,内分泌代谢病学,1986年

同被引文献34

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