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瞬目反射在糖尿病神经病变中的诊断价值

Diagnostic value of blink reflex in diabetic neuropathy
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摘要 目的 观察糖尿病 (DM )患者瞬目反射 (BR)的变化 ,了解BR对糖尿病中枢神经病变的诊断价值。方法 于眶上切迹处以方波脉冲电刺激眶上神经 ,记录双侧眼轮匝肌的反应 ,测定刺激同侧所记录的R1、R2 波和对侧R′2 波的潜伏期及波幅变化。结果 DM患者的R1、R2 和R′2 波的潜伏期较对照组明显延长 ,其波幅较对照组明显降低 ;随糖尿病病程的延长BR的异常率逐渐升高。结论 BR检查可作为糖尿病患者神经受损的客观指标 。 Objective To understand the diagnostic value of blink reflex (BR) in central neuropathy by observing the variations of blink reflex in diabetic patients. Methods Electrical pulse was used to stimulate the supraorbital nerve at the supraorbital notch. The responses of bilateral orbicular muscles of the eye were recorded, the variations of the latency and amplitude of R 1 and R 2 recorded on the side of stimulation and of R′ 2 recorded on the contralateral side were measured. Results There was significant prolongation in the latency and lowering of the amplitude of R 1, R 2 and R′ 2 in the diabetic patients compared with the control group. The abnormality rate of BR increased gradually with the prolongation of diabetic duration. Conclusion BR examination might provide an objective index for nervous damage in diabetic patients and it is helpful in early diagnosis of diabetic neuropathy.
出处 《西安交通大学学报(医学版)》 CAS CSCD 北大核心 2004年第2期142-143,146,共3页 Journal of Xi’an Jiaotong University(Medical Sciences)
关键词 瞬目反射 糖尿病 诊断 中枢神经病变 眼轮匝肌 diabetes mellitus blink reflex neuropathy
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