摘要
本文应用ICP-光谱法对50例消化道肿瘤病人的血清锌、铜及铜/锌比值作了对照性观察、结果表明肿瘤病人的血清锌低于对照组、血清钢及铜/锌比值高于对照、差异非常显著(P<0.001、P<0.005)。有远位转移组与无转移组相比;静脉营养组与进食组相比,血清锌、铜及铜/锌比值差异不显著(P>0.05～0.10)。因此,认为血清锌低、铜及铜/锌比值增高是本组肿瘤病人的特征,可作为肿瘤监测的一个指标,但是,不能作为判断预后的依据。
The serum zinc and copper levels were determined with ICAP-9000 in 50 cases of advanced gastrointestinal cancer (7 esophageal cancer, 33 gastric cancer, 10 large bowel cancer). The serum zinc level was significantly lower (P< 0.001), the serum copper level and the Cu/Zn ratio were significantly higher (P<0.005,P<0.001)in patients with gastrointestinal cancer than that in the control group. There was no significant difference between patients of parenteral nutrition group and those of the per os nutrition group in terms of serum zinc and copper levels and Cu/Zn ratio. The same result was found in comparing metastasized patients with nonmetastasized group. These results suggest that changes of the serum zinc and copper levels and Cu/Zn ratio could be a basic feature in patients with gastrointestinal cancer, but might not be able to provide sound basis in the assessment of outcome of patients with gastrointestinal cancer.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1992年第4期299-300,共2页
Chinese Journal of Clinical Oncology
关键词
消化道肿瘤
血清锌
血清铜
Gastrointestinal cancer
Serum zinc
Serum copper
Serum Cu/Zn ratio
