摘要
本文分析了19例22例次各类骨髓供体的自身状况,重点讨论了供体髓采集质量及并发症,并与正常供体作了比较。结果表明,骨髓采集的部位选择,麻醉选择及骨髓采集量均无自身影响并且可直接进入BMT。并认为多次供髓,其间隔时间越长对有核细胞数影响越小。22例次发生并发症10次。FUO在自体供者中易发生(13％)。所有并发症均历时短暂,可迅速恢复。7例次异体正常供者血液学随访1～3年无异常。对今后临床BMT工作提供了参考依据。
The after-effect of 22 marrow aspirations on 19 donors are analyzed with an emphasis on the quality of marrow harvested and complication.Results obtained from autologous marrow transplantation (AMT) are compared with those from allogeneic donors.Ten complications were observed following 22 marrow aspirations.The incidence of fever of unknown origin (FUO) in AMT was high (13%).The durations of the complications were very short.The puncture site,anesthesia mode and aspirated marrow magnitude resulted in no adverse effects on the donors.Marrow could be transfused immediately after collection.When more than one aspirations were performed in the same donor,the longer the interval,the less the effect on concentration of marrow nucleated cells harvested.In 7 allogeneie donors followed up for 1-3 years nohematological abnormality was found.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1992年第3期171-173,共3页
Chinese Journal of Clinical Oncology
关键词
骨髓移植
骨髓供体
并发症
Bone marrow transplantation
Marrow donor
Complication
