摘要
我院于1980～1987年对食管癌术后吻合口局部复发患者11例进行了再次手术切除,8例行局部放疗,3例先行放疗后再手术切除;对20例根治性放疗后局部复发者行手术切除。42例患者半数再获2年以上生存。再次手术对仅为吻合口局部复发不伴远处转移者为可行之方法,半数获2年以上生存期,并有5年以上生存之病例。但再手术前须慎重选择适应症,排除临近组织受侵及远处转移,术中应细心操作,对粘连严重者尤须注意,勿损伤其他器官。局部放疗对吻合口复发有一定效果,但疤痕组织中的乏氧癌细胞不易被彻底杀灭。术前先行放疗对清除癌周淋巴结有所补益。根治性放疗后局部复发与放射性纤维化或放射性溃疡不易鉴别,且多数人认为再程放疗效果不佳。对解除放疗后狭窄,手术切除仍是可行之方法。
Forty two patients with recurrent esophageal cancer were treated in our hospital from 1980-1987.In 12 patients the recurrence was at the anastomotic site.Of this series 11 were re-operated,8 were irradiated,and 3 were re-operated after irradiation.Twenty patients of this series who had cancer recurred in the esophagus after radical radiotherapy were treated by surgical resection.Half of the patients survived for over 2 years.Operation for recurrent tumor should be done only in cases without distant metastasis.Radiotherapy was effective for those recurrent lesion occurring at the anastomotic site,but there was difficulty in destroying the anoxic cancer cell in the scar.The patients with recurrent cancer after radical radiotherapy were treated by surgical resection,but postoperative complications were more frequent.Theshorter the period before recurrence,the worse the treatment result would be.Theauthors believe that surgical resection is good for stricture and obstruction causedby recurrent cancer following radiotherapy.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1992年第2期105-107,共3页
Chinese Journal of Clinical Oncology
关键词
食管肿瘤
继发性
Recurrent esophageal carcinoma
Treatment
