摘要
首次从亚细胞水平证实沙棘与维生素E相似,对高脂血清损伤的干滑肌细胞有如下的保护作用:1.降低细胞内脂质过氧化物含量;2.减轻细胞膜的损伤;3.保护细胞健康生长并促其增生。
The effect of Hippophae rhamnoides on hyperlipidemicrabbit sernm(HRS)cultured smooth muscle cells(SMC)was observed in comparison with vitamin E(VE).The results show that Hippophae rhamnoides, much like VE, is also a potent antioxidant. It strongly decreases the MDA content in HRS cultured SMC and protect the cells from the injury of lipid peroxidation, and thus keeps the SMC growing and proliferating healthily. The results implicats that Hippophae rhamnoides is an effective antioxidant, and one of the important mechanisms of Hippophae rhamnoides in anti-atherosclerosis reported recently may be closely related to the action of anti-lipid peroxidation.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1992年第10期624-626,共3页
China Journal of Chinese Materia Medica
关键词
沙棘
平滑肌细胞
高血脂病
Hippophae rhamnoides
smooth muscle cell
atherosclerosis, lipid peroxidation, hyperlpidemia
