摘要
实验结果表明,丹参能明显抑制正常及损伤肝细胞脂质过氧化反应,诱导细胞色素P450的合成,防止损伤肝细胞蛋白质、DNA、RNA、尿素及铜兰蛋白的降低,减轻肝毒物对体外培养肝细胞超微结构的损伤。
The results indicated that RSM could significantly inhibit the lipid peroxidation of normal livers and cultured hcpatocytes of rats, induce liver microsomal cytochrome P_(450) in normal rats, increase nucleic acids, proteins, urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ultrastructural damage of cultured hepatocytes induced by CCl_4. The pharmacological actions mentioned above should be considered as important mechanisms of RSM against liver iniury.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1992年第4期233-236,共4页
China Journal of Chinese Materia Medica
基金
山西省科研基金
关键词
肝
丹参
脂质过氧化作用
liver
Radix Salviae Miltiorrhizae
lipid peroxidation
