摘要
目的 探讨Duchenne进行性肌营养不良症肌肉声像图的特点及其诊断价值。方法 应用高频超声检测 81例Duchenne进行性肌营养不良症患者下肢肌肉。按照年龄分为 4组 :3～ <7岁 13例 ,7～ <10岁 3 0例 ,10～ <13岁 3 0例 ,13～ 14岁 8例。选择 1～ 11岁健康儿童 2 0例作为对照组。依次对臀部、大腿部、小腿部肌肉行纵横切位超声扫查。结果 患者 3岁时 ,臀肌萎缩 ,皮下脂肪增厚 ;随着年龄的增长 ,臀肌、大腿部位肌肉、小腿肌肉和背肌萎缩呈现进行性加重 ,皮下脂肪增厚 ,各年龄组差异有显著性意义 (P <0 .0 1)。结论 高频超声可为Duchenne进行性肌营养不良症的诊断、病情随访和临床病理活检提供客观依据。
Objective To evaluate the value of high-frequency ultrasound for diagnosing Duchenne muscular dystrophy.Methods Eighty-one cases with Duchenne muscualr dystrophy were divided into four groups according to their age,age 3-7(13 cases),age 7-10 (30 cases), age 10-13 (30 cases),age 13-14 (8 cases). Twenty cases of healthy children, aged from 1 to 11 were chosed as controls. In all groups' buttock muscle,thigh and leg muscle were observed by high-frequency ultrasound longitudinally and horizontally.Results Gluteus atrophy and subcutaneous fat thickening were seen in age 3 patients,progressive subcutaneous fat thickening and progressive muscular atrophy of buttock,thigh and leg with age were proved.There were significantly differences among groups ( P < 0.01 ).Conclusions High-frequency ultrasound has an objective criterion on the follow-up,clinical pathology and diagnosis of Duchenne muscular dystrophy.
出处
《中华超声影像学杂志》
CSCD
2003年第9期548-551,共4页
Chinese Journal of Ultrasonography
