摘要
本文介绍了用高效液相测定奎尼丁(Quinidine)血药浓度,以辛可宁(Cinchon-ine)为外标,水:乙腈(91:9v/v)为流动相。奎尼丁出峰时间6.6min,辛可宁出峰时间3.8min,检测最低浓度0.1μg/ml,线性范围为1～16μg/ml。
This artical introduces a method for determination of quinidine in plasma by
HPLC. Cinchcnine was used as infernal standard. water: acetonitrile as mobile
phase. The retention time is quinidine 6.6 min, cinchonine 3.8 min. The minimun
concentration determined was 0.1μg/ml. The linear range was 1～16μg/ml.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1992年第1期14-16,共3页
Chinese Journal of Hospital Pharmacy
