摘要
目的 探讨低水平 β HCG滋养细胞肿瘤的临床特点、诊断及对策。 方法 回顾性分析汕头大学医学院第一附属医院 1 991年 1月至 2 0 0 3年 1月间 6例低水平β HCG滋养细胞肿瘤的临床特点及诊治经过。 结果 6例中侵蚀性葡萄胎 3例 ,绒癌 2例 ,胎盘部位滋养细胞肿瘤 (PSTT) 1例。先行妊娠葡萄胎 3例 ,足月产 3例 ;先行妊娠至诊断时间 2～ 1 8个月 ;5例主要表现为不规则阴道出血 ,5例超声提示滋养细胞肿瘤 ;血 β HCG 1 1～2 7IU/L。结论 低水平 β HCG滋养细胞肿瘤可能与滋养细胞的类型及分布有关 ,其临床特点主要为不规则阴道出血 ,超声是诊断及鉴别诊断的主要手段 ,早期诊断。
Objective To explore the clinical characteristics,diagnosis and treatment of gestational trophoblastic tumor(GTT)with low level β human chorionic gonadotropin (β HCG).Methods Six cases of GTT with low level β HCG treated in the First Affiliated Hospital,Medical College of Shantou University from January 1991 to January 2003 were retrospectively analyzed for the clinical manifestations and the experience of diagnosis and treatment.Results Among the 6 cases,3 were invasive mole,2 choriocarcinoma and 1 placental site trophoblastic tumor.Antecedent pregnancies were hydatidiform mole (3 cases) and term pregnancy(3cases).The period of antecedent pregnancy to the presentation of GTT was 2～18 months.The main symptom was irregular vaginal bleeding in 5 cases.Ultrasound showed GTT in 5 patients.The level of β HCG was 1 1～2 7IU/L.Conclusion The etiology of low level β HCG in GTT may be related to the distribution and the type of trophoblastic cell.The main symptom is irregular vaginal bleeding.Coloured Doppler echography is a main method for both diagnosis and differential diagnosis.Early diagnosis and treatment may prevent the disease from worsening.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2004年第4期226-227,共2页
Chinese Journal of Practical Gynecology and Obstetrics
