摘要
目的 探讨颞下颌关节双板区在关节盘移位后的适应性改建。方法 采用组织化学和原位杂交的方法 ,对 2 6只日本大白兔进行组织病理学、蛋白多糖含量和Ⅱ型胶原基因表达变化的研究。结果 移位 1周后即在双板区见到有Ⅱ型胶原mRNA表达的软骨细胞 ,随着时间的增加 ,可见到典型的软骨组织形成。结论 在关节盘移位后 ,双板区产生类盘样变 。
Objective To study the adaptive alteration in bilaminar zone of rabbits′ temporomandibular joint following disc displacement Methods Twenty six Japanese white rabbits were used in this study Among these rabbits,6 were used as controls The right discs of other 20 rabbits were displaced anteriorly by operation Four of these rabbits were killedatn 1? 2? 4? 6 and 8 weeks respectively after surgery The TMJS were studied by HE staining, Alcin bluen staining and in situ detection of type Ⅱ collagen mRNA expression Results There appeared cartilage metaplasia after one week following disc displacement Typical chondrocytes could be found in the bilaminar zone The new chondrocytes expressed type Ⅱcollagen Conclusions The bilaminar zone of TMJ will be remodeled following disc displacement and become a disc like tissue to function as a disc
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2003年第4期292-294,I006,共4页
Chinese Journal of Stomatology
