摘要
利用细胞培养技术观察人参茎叶皂甙(GNS)及Rb_1等单体对病毒感染细胞的保护作用。结果表明:GNS有明显的抑制HSV—I、HSV—Ⅱ、ADV—Ⅲ及VSV病毒在细胞内复制的作用,使细胞受到保护;其有效单体以Rb族为主。用含GNS霜剂对31例HSV—Ⅰ感染的口唇疱疹和口腔溃疡患者进行涂敷治疗,治愈27例(占87.10％)。本实验结果为临床应用GNS治疗某些病毒性疾病提供了一定的实验依据。
The protection of ginseno-side (GNS ) isolated from leaves and stems on cultured cell from virus were observed. The results showed that GNS, especially the Rb1 monomer could suppress replication of virus such as HSV -Ⅰ , HSV-Ⅱ ,ADV- Ⅲ and VSV, and protect the cultured cells from virus infec-
tion. A cream containing GNS was used in the treatment of herpes lebialis infected by HSV- I and 27 of 31 (87. 1%) cases were cured.
出处
《中国药理学通报》
CAS
CSCD
北大核心
1992年第3期221-224,共4页
Chinese Pharmacological Bulletin
