摘要
报道苯妥英(PHT)外用治疗难愈性创面12例,取得良好疗效。12例病人均经采用常规换药治疗或手术植皮失败,创面不愈1月以上者。包括:慢性骨髓炎溃疡,放射性溃疡,神经肌腱暴露的溃疡,手术后伤口不愈的潜腔性溃疡,烧伤残余创面。溃疡面积为3×3～10×13cm,平均6×7cm。烧伤残余创面为1％～9％,平均5％。经PHT外用创面换药后,8例创面自行愈合,4例植皮后迅速愈合。
Twelve intractable wounds had been treated with topical pure phenytoin powder since October, 1989. The result was excellent. The cases treated induded chronic ulceration of low extremity, post irradiation ulcers and residual wounds from burn. The surface area of ulcers varied from 3×3cm to 10×13cm, a mean of 6×7cm; the residual wound from burn from 1% to 9%, a mean of 5%. The traditional therapy or skin graft both failed to give any healing of the wounds. The duration of the wound existed from 1 month to 20 years. After topical phenytion, 8 cases intractable lesions healed completely and 4 with the combination of skin graft. The mean time for wound healing was 29.37 days. The method, results and the mechanism of enhancement of healing of intractable lesions from topical phenytoin discussed.
出处
《中国修复重建外科杂志》
CAS
CSCD
1992年第1期16-17,共2页
Chinese Journal of Reparative and Reconstructive Surgery
关键词
苯妥英
难愈性
创面
Phenytoin Intractable lesion
