摘要
目的 :观察全反式维A酸 (ATRA)诱导分化治疗急性早幼粒白细胞性白血病 (APL)诱发高危并发症的过程 ,为早期诊断和治疗提供依据。 方法 :对初发的 1 0例APL患者的临床资料采用统一表格进行登记和分析。 结果 :诱导期危及生命的主要并发症是白细胞 (WBC)增多症和维A酸综合征 (RAS) ,发生率分别为 90 %和 1 0 %。结论 :在ATRA治疗中 ,要密切观察患者临床表现和WBC计数等 ,及时用药 。
Objective: To observe the precess of evoking high risk complications when using ATRA to induce differentiation therapy acute promyelocytic leukemia(APL),to provide criteria which could be useful for earlier diagnosis and therapy. Methods: Ten patients with primary APL and clinical data was assessed with unification centification. Results:In the induction period the main complications which would be dangerous for the life ,were hyperleucocytosis symptom and RAS,and their incidence were 90% and 10% separately. Conclusion: In the period of therapy using ATRA,we should pay close attention to the clinical situation and leucocyte number,and medicating on time,in order to save the patients’ life.
出处
《医学研究生学报》
CAS
2003年第12期903-905,共3页
Journal of Medical Postgraduates
基金
南京军区南京总医院青年基金资助项目 (批准号 :0 980 0 6)
关键词
维A酸
白血病
并发症
护理
Retinoic acid promyelocytic
Leukemia
Complication
Nursing
