摘要
目的研究蚕蛹复合氨基酸促进外伤大鼠创口愈合的作用和对自由基的影响。方法本文通过将大鼠造成外科创伤模型后,以蚕蛹复合氨基酸给药14天,观察动物一般情况、皮肤张力、创口皮肤羟脯氨酸含量、血清SOD、MDA、GSH-PX等指标。结果蚕蛹复合氨基酸能明显提高创伤大鼠皮肤张力、创口皮肤羟脯氨基酸含量,升高SOD、GSH-PX含量,降低MDA含量。结论蚕蛹复合氨基酸能明显促进外伤大鼠创口愈合并具清除自由基作用。
Objective The effect of co-amino acids extracted from silkworm chiysalis on concrescence of wound and the free radical in surgical hurted rats were studied.Methods The mode of rats were made by surgical operating.The rats' condition,tensile force of skin,concentration of HYP in the wounded skin,SOD,MDA and GSH-PX were observed after feeding co-amino acids extracted from silkworm chrysalis for 14 days.Results The co-amino acids extracted from silkworm chrysalis could obviously improve tensile force and concentration of HYP of the wounded skin,heighten the content of SOD,GSH-PX and lower the content of MDA.Conclusion The co-amino acids extracted from silkworm chrysalis had the effect of accelerating the wound's concrescence and has the effect of clearing free radical.So we should make the best use of silkworm chrysalis.
出处
《医学研究通讯》
2004年第3期43-45,共3页
Bulletin of Medical Research
关键词
蚕蛹
复合氨基酸
创伤
创口愈合
自由基
Silkworm chrysalis Teh co-amino acids Concrescence of wound Free radical
