摘要
目的 :观察慢性冠心病与肺炎衣原体感染的关系。方法 :应用间接微量免疫荧光法测定慢性冠心病 74例 (冠心病组 )与健康人 72例 (对照组 )血清中肺炎衣原体IgG、IgM的抗体滴度。 结果 :两组的血清肺炎衣原体IgG抗体滴度差异有非常显著性 (P <0 .0 1) ,对照组与冠心病组肺炎衣原体总感染率分别为 72 %与 10 0 %,其中既往感染率分别为 72 %与80 %,急性感率分别为 0 %与 2 0 %。结论 :慢性冠心病患者肺炎衣原体感染率增高 ,肺炎衣原体感染可能是冠心病发生的致病因素之一。
Objective:To observe the incidence of Chlamydia pneumoniae (Cpn)infection in patients with chronic coronary heart disease(CCHD).Methods:Serum IgG and IgM antibodies to Cpn were determined by indirect microimmunofluorescence assay in 74 patients with CCHD and 72 health controls.Results:The total infection rates in controls and patients were 72% and 100% respectively( P <0.01);among them,the previous infection rates were 72%and 80%,and the acute ones were 0% and 20%( P <0.01),respectively.The titre of IgG antibody was significantly higher in patinents than that in controls( P <0.01).Conclusion:The incidence of CP infection increases in patients with CCHD,and Cpn infection may be a risk factor in the development of CCHD.
出处
《广东医学院学报》
2004年第2期135-136,140,共3页
Journal of Guangdong Medical College
关键词
衣原体
肺炎
荧光抗体技术
冠状动脉疾病
chlamydia pneumoniae
fluorescent antibody technique
coronary disease
