摘要
F Ⅴ Leiden突变可导致活化蛋白C抵抗现象,是引起白种人静脉血栓栓塞的最常见遗传因素。但对这一突变与缺血性卒中的关系尚存有争议。文章综述了F Ⅴ Leiden突变的分子机制及近年来在缺血性卒中方面的研究情况。
Factor Ⅴ Leiden mutation can cause the phenomenon of activated protein C resistance. It is the most common genetic factor for venous thromboembolism in the white population. However, the relationship between factor Ⅴ Leiden mutation and ischemic stroke remains controversial. The article reviews the molecular mechanism of factor Ⅴ Leiden mutation and the recent findings in ischemic stroke.
出处
《国外医学（脑血管疾病分册）》
2004年第3期231-233,共3页
Foreign Medical Sciences Cerebrovascular Diseases
