摘要
目的采用回顾性分析方法 ,通过对69例脑梗死住院死亡病例与存活病例进行1∶1配对的病例对照研究 ,探讨血液流变学异常对脑梗死转归的影响 ,以便对高危因素及时予以干预。方法血液流变学数据资料源于住院病历。采用仪器MVIS -2010全自动血液流变分析系统。统计软件为SAS6.12,作配对t检验 ,条件logistic回归分析。结果与生存的脑梗死组比较 ,死亡组的全血黏度增加 (P<0.05) ,红细胞聚集性增强(P=0.001) ,纤维蛋白原浓度上升(P=0.001) ,相对危险度(RR)均大于1。结论全血黏度增加 ,红细胞聚集性增强 ,纤维蛋白原浓度上升 ,与脑梗死病人的死亡事件显著相关。纤维蛋白原是预测脑梗死死亡事件的独立预测因子。
Objective To investigate the effect of abnormal hemorrheology to the conversion of cerebral inˉfarction.Sixty_nine cases of patients died from cerebral infarction were retrospectively studied through case_study method.Methods Laboratory paramaters were derived from medical history.Results The whole blood viscosity,RBC aggregation,the concentration of fibrinogen and RR in death group were markedly increased than that in conˉtrol group.Conclusions The results suggest that the increase of whole blood viscosity,RBC aggregation and the concentration of fibrinogen are markedly correlated with the death events of cerebral infarction patients.Fibrinogen is an independent factor of the death event of cerebral infarction patients.
出处
《中国微循环》
2004年第2期107-108,共2页
Journal of Chinese Microcirculation
