摘要
本文应用斑点杂交试验直接检测101例乙肝病毒(HBV)无症状携带者、慢活肝及肝硬化患者血清HBV DNA,阳性率分别为58.3％(21/36)、36.9％(17/46)、10.5％(2/21),三组间有显著差异(P<0.01)。并与血清免疫标志进行比较,在HBeAg阳性时,HBV DNA检出率分别为95.2％(20/21)、70.8％(17/24)、25.0％(1/4),三组间有显著差异(P<0.05)。HBsAg、抗-HBc及抗-HBe与血清HBV DNA并非一致。结果表明,HBV无症状携带者比慢活肝及肝硬化具有更高的传染性,是极重要的传染源。
One hundred and one patients with HBV asymptomatic carrier, chronic active hepatitis (CAN) and liver cirrhosis were assayed for HBV DNA with direct spot hydridization. HBV DNA positive rates were58.3% (21/36), 39.6% (17/46) and 10.5% (2/21), respectively. There was significant difference among three groups (p<0.01). HBV DNA positive rates were 95.2% (20/21), 70.8% (17/24) and 25.0% (1/4) , respectively, when HBeAg was positive. There was significant difference among three groups (p<0.05). It is not accordant that HBsAg, anti-HBc and anti-HBe were compared with serum HBV DNA. These results indicate that HBV asymptomatic carriers are more infectious than CAH and liver cirrhosis. They are extremely infectious sources.
出处
《安徽医学》
北大核心
1989年第4期5-6,共2页
Anhui Medical Journal
