摘要
目的观察酵母样真菌对氟康唑的耐药趋势。方法用E-test方法监测2003年酵母样真菌对氟康唑的最低抑菌浓度和耐药趋势。结果 2003年临床常见的1449株酵母样真菌对氟康唑的耐药率分别为:白色假丝酵母菌4.1％、热带假丝酵母菌6.1％,近平滑假丝酵母菌11.2％,光滑假丝酵母菌45％,克柔假丝酵母菌66.7％。结论氟康唑对白色假丝酵母菌、热带假丝酵母菌、近平滑假丝酵母菌仍保持较高的抗菌活性,而光滑假丝酵母菌、克柔假丝酵母菌对氟康唑的耐药率较高。
Objectives To monitor the resistant trend of yeast to Fluconazole. Methods To monitor the susceptibility trend of yeast to Fluconazole in 2003 with E-test. Results The resistant rate of 1449 Yeast in 2003 respectively is; Candi- da albicans is 4.1％, Candida tropicalis is 6.1％, Candida parapsilosis is 11.2％, Candidaglabrata is 45％ and Candida Krusei is 66.7％. Conclusion Fluconazole keeps high activity to Candida albicans, Candida tropicalis and Candida parapsilosis. but Fluconazole have high resistant rate to Candida glabrata and Candida Krusel. That is the same as some report.
出处
《临床药物治疗杂志》
2004年第2期48-50,共3页
Clinical Medication Journal
