摘要
目的 了解鼻咽癌患者鼓室导抗图峰压值在放疗前后的变化规律及对听力变化的影响。方法 追踪观察 32例 (6 4耳 )接受常规放射治疗的鼻咽癌患者 ,在放疗前、放疗中、放疗结束、放疗后 6个月、放疗后 12个月对其进行纯音听阈及声导纳测试。结果 放疗后一年内有 9耳发生分泌性中耳炎 ,其中有 6耳发生于放疗结束时。余 5 5耳的鼓室导抗图峰压值在放疗开始后呈负压 ,在放疗结束时最为严重 ,平均为 - 30 (- 10 0 ,5 .0 )daPa ,与放疗前有明显统计学意义 (P <0 .0 1) ,但可逐渐恢复 ,在放疗后 12个月明显恢复到放疗前水平 5 .0 (- 2 .5 ,10 ,0 )daPa ;5 5耳放疗结束时 2 .0kHz骨导听阈平均为 2 1.4± 5 .7dB ,与放疗前相比有明显的下降 ,并有统计学意义 (P <0 .0 1)。结论 放射治疗鼻咽癌可影响咽鼓管功能 ,常合并有分泌性中耳炎 ;即使未合并有分泌性中耳炎的照射耳 ,其鼓室导抗图峰压值在放疗前后也呈明显波动性变化 ,以在放疗结束时最为明显 ,并对 2 .
Objective To explore the changes of the peak pressure of tympanogrom in the first year before and after radiotherapy for Nasopharyngeal Carcinoma (NPC) and observe its effect to audition.Methods Acoustic immittance and audiometry were used to detect 64 ears of NPC patients at regular intervals (before, during,at the end of rediotherapy and 6,12 months after radiotherapy). The data were collected and analyzed with statistic methods. Results There were 9 ears with secretory otitis media after radiotherapy. The peak pressure of tympanogrom of other 55 ears was negative at the beginning of radiation, reached highest at the end of radiotherapy,the average was -30(-100, 5.0) daPa.Compared with the peak pressure of tympanogrom before radiation, there was significant statistic difference ( P =0.001). The peak pressure reached to the level of pre-radiation 12 months after radiation, 5.0(-2.5,10.0) daPa. The 2.0 kHz audiometric threshold of bone conduction was 21.4±5.7 dB in 55 ears, compared with the audiometric threshold before radiation, there was evident statistic difference (P<0.01). Conclusion There was evident changes of peak pressure of tympanogrom in the first year after radiotherapy for NPC and the radiotherapy effected 2.0 kHz audiometric threshold of bone conduction.
出处
《听力学及言语疾病杂志》
CAS
CSCD
2004年第2期89-90,100,共3页
Journal of Audiology and Speech Pathology
关键词
鼓室导抗图峰压值
听力
放射治疗
鼻咽癌
The peak pressure of tympanogrom
Audition
Radiotherapy
Nasopharyngeal carcinoma
