摘要
近年来研究资料表明,主要调节血压、内分泌和植物性功能的加压素(Vasopressin,VP)也参与痛觉调制。脑室内注射VP可产生明显的镇痛作用,相反。
In this experment, the role of PVN in acupuncture analgesia was further investigated with electrophysiological technique. In wistar rats the unit discharge was recorded extracellularly, Noxious stimulation was applied to sciatic nerve, and the electroacupuncture was performed on acupoints 'Zusanli' and 'Sanyinjiao'. Totally eighty-two units were recorded successfully from PVN. 49 units of them reacted to electroacupuncture with excitatory (14), inhiditory (23) or on significant effect (12). Various types of reactions including excitation (12), inhibition (6),excito-inhibition (4) or inhibito-excitation (3) were observed on 43 units during noxious stimulation of sciatic nerve. The remainder 18 units had no significant reaction. After electroacupuncture those units reacting with excitatory effect on noxious stimulation decreased their firing rate, and those with inhibitory effect increased their firing rate. The duration of nociccptive reaction was shortened after electroacupuncture in both types of units. It was suggested that electroacupuncture could influence the activities and decrease the nociceptive reactions of PVN neurons, which might be considered as electrophysiological evidence of the involvement of PVN in acupuncture analgesia.
出处
《针刺研究》
CAS
CSCD
1992年第3期161-165,共5页
Acupuncture Research
基金
江苏省科委资助项目
