摘要
目的 :了解抑郁症患者局部脑血流灌注的特点。 方法 :应用单光子发射计算机断层扫描对 2 0例抑郁症患者及 18例正常对照者局部脑血流灌注进行对比分析。 结果 :抑郁症组双侧基底核、双侧额叶、左颞叶及左枕叶局部血流低灌注 ;抑郁症组与对照组左右大脑半球局部血流灌注无显著性差异。 结论 :抑郁症患者局部脑血流存在低灌注 。
Objective:To understand the characteristic of regional cerebral blood flow (rCBF) in major depression. Method:Twenty patients with major depressive disorder were studied at rest using SPECT in comparison with 18 normal controls. Results: The depressed group showed lower rCBF in bilateral basal ganglia and frontal lobes,left temporal lobe and occipital lobe than normal controls.Lateralization of hypoperfusion was not supported by our study. Conclusion:There was a lower perfusion of regional cerebral flow,but there was not a lateralization of hypoperfusion in major depression.
出处
《临床精神医学杂志》
2004年第1期12-13,共2页
Journal of Clinical Psychiatry
基金
苏州大学附属第一医院科技基金课题 (H983 6)
关键词
抑郁症
局部脑血流
单光子发射计算机断层扫描
Major depression
Regional cerebral blood flow
Single photon emission computedtomograpy
