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生物杀虫剂多杀菌素的中毒症状和作用机理 被引量:17

Poisoning Symptom and Mode of Action of Bioinsecticide Spinosad
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摘要 生物杀虫剂多杀菌素是一类全新的杀虫剂,它具有神经毒剂特有的中毒症状,表现为身体的上升,非功能性肌肉收缩和震颤,最终衰竭,瘫痪。其作用机制是通过激活烟碱型受体使昆虫神经细胞去极化,引起中央神经系统广泛的超活化。多杀菌素也通过抑制γ-氨基丁酸受体而使神经细胞超活化。本文就是对多杀菌素中毒症状和作用机理的研究进展作一综述。 bio-insecticide spinosad is a novel insecticide which shows the special neurotoxic poisoning symptom with an elevation of the body, involuntary muscle contractions and tremors, eventually prostrate and paralyzed. Spinosad depolarizes insect neurons by activating nicotinic receptors, causing widespread hyperactivity in the nervous system. Spinosad also act at γ-aminobutyric acid recepors by inhibiting g-aminobutyric acid recepors to lead neurons hyperactive. This paper reviewed the mode of action of spinosad.
出处 《农药科学与管理》 CAS 2004年第2期25-28,共4页 Pesticide Science and Administration
关键词 生物杀虫剂 多杀菌素 中毒症状 作用机理 烟碱型受体 spinosad poisoning symptom nicotinic receptors γ-aminobutyric acid receptors.
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参考文献6

  • 1Salgado VL, Sheers JJ,Watson GB et al. Studies on the mode of action of Spinosad: the internal effective concentration and the concentration dependence on neurel excitation,pesticide biochemistry and physiology, 1998 (60): 103 - 110.
  • 2Vincent L Salgado, Studies on the mode of action of Spinosad: insect symptoms and physiological correlates, pesticide biochemistry and physiology 1998(60):91-102.
  • 3Salgado V L, The mode of action of spinosad and other insect control products, Down to Earth, 1997(52): 35-44.
  • 4Gerald B. Watson, Action of insecticidal spinosyns on gaminobutyric acid responses from small-diameter cockroach neurons, pesticide biochemistry and physiology 2001 (71),20-26.
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