摘要
目的 观察急性心肌梗死患者冠状动脉介入 (PCI)治疗成功后 ,校正的TIMI帧数(CTFC)与心电图ST段回落联合评价心肌组织水平灌注的可行性。方法 测定PCI治疗后血流达TIMI 3级患者的CTFC ,并在术前及术后 1个月分别测定室壁运动记分 (WMSI)。观察CTFC与WMSI之间的相关性 ,同时检查术前及术后 1小时心电图ST段回落情况。结果 按照CTFC将TIMI血流3级者分为快、慢两组 ,快CTFC组患者ST段回落程度明显优于慢CTFC组 ;1个月后快CTFC组患者的室壁运动记分改善程度明显优于慢CTFC组 ,CTFC与术前、术后WMSI的差值有明显的负相关 ;快CTFC组患者从发病到接受PCI治疗的时间明显短于慢CTFC组。结论 CTFC作为一种定量、客观、简单、经济、重复性好的方法评价心肌微循环灌注情况 ,较低的CTFC及心电图ST段回落完全预示着良好的心功能恢复 。
Objective To study the probability of evaluating myocardial tissue perfusion by corrected Thrombolysis In Myocardial Infarction (TIMI) frame count (CTFC) and the grade of ST segment resolution after successful percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).Methods To measure CTFC after successful PCI in 63 patients with their first AMI and to analyse the extent of ST-segment-elevation resolution 1 hour after reperfusion therapy.To assess wall motion score index (WMSI) by two-dimentional echocardiography before and one month after PCI and study the correlation between CTFC,ST segment resolution and WMSI.Results According to CTFC the patients were divided into two groups.TIMI 3 fast group had higher percentage of complete ST resolution and lower percentage of no ST resolution.Improvement of WMSI in the TIMI 3 fast group was significantly greater than that of the TIMI 3 slow group.CTFC had a significant correlation with the change in WMSI.Elapsed time from the onset of symptoms to reperfusion in the TIMI slow group was significantly longer than that of the TIMI fast group.Conclusion CTFC is a quantitative,objective, realistic index of coronary blood flow.Combined with electrocardiogram ST-segment resolution,CTFC could predict risk for patients with successful reperfusion therapy after AMI and supply evidence for additional adjunctive treatment.
出处
《临床内科杂志》
CAS
北大核心
2004年第3期171-173,共3页
Journal of Clinical Internal Medicine
关键词
校正TIMJ帧数
室壁运动记分
心肌梗死
冠状动脉介入治疗
心肌组织水平灌注
Corrected TIMI frame count
Wall motion score index
Myocardial Infarction
Percutaneous coronary Intervention
Myocardial tissue perfusion
