摘要
[目的 ]探讨高血压病人血压变异性与早期心脏损害的关系及护理。[方法 ]对 40例高血压病人和 2 1例正常对照组行2 4h动态血压监测(ABPM ) ,以各时间段血压的标准差作为血压变异性指标 ,并测定左心室心肌重量指数 (LVMI)和血清Ⅲ型前胶原 (PCⅢ )浓度。 [结果 ]高血压病人各时间段长时血压变异性较对照组显著增大 (P <0 .0 1) ,高血压组LVMI、PCⅢ浓度与对照组比较有统计学意义 (P <0 .0 5 ) ,且LVMI和PCⅢ与各时间段血压变异性显著相关 (P <0 .0 5 )。 [结论 ]长时血压变异性可能与左心室肥厚有关 ,有效控制血压 。
Objective: to probe into the relationship between blood pressure variability and early stage heart damage of hypertension patients and nursing care of them. Method: a total of 40 cases of hypertension and 21 cases of normal individuals were selected and as test and control groups. 24-hours automatic blood pressure monitoring (ABPM) of them had been performed. Standard difference of blood pressure in different time period was taken as their blood pressure variability index. Meanwhile, both left ventricle myocardial-weight index (LVMI) and plasma type Ⅲ precollagen (PC Ⅲ) concentration of patients had been determined. Results: long term blood pressure variability of each time period in hypertension patients extended more remarkably than that in control group (P<0.001). There were statistical significant differences compared both LVMI and PC Ⅲ concentration of test group patients with that of control group (P<0.05). Moreover, both LVMI and PC Ⅲ concentration of test group patients were significantly correlated with their blood pressure variability in each time period (P<0.05). Conclusion: long term blood pressure variability of hypertension patients possibly related with their left ventricle thickening. Therefore, both to control blood pressure effectively and to reduce the blood pressure variability in hypertension patients could abate their left ventricle thickening.
出处
《护理研究》
2004年第3期410-412,共3页
Chinese Nursing Research
关键词
血压变异性
心肌损害
高血压
blood pressure variability
myocardial damage
hypertension