摘要
虽然自从20世纪50年代开展同种异体肾移植以来,终末期肾病(ESRD)的预后明显改善,但该人群的期望寿命仍明显低于一般人群.
Objective To compare the efficacy and toxicity of in patients with advanced colorectal cancer. Methods Seventy-six patients were enrolled in this study.38 patients(treatment group)received chemotherapy regimen of sodium cantharidate 0 3mg,CF 200mg/m 2, and 5-Fu 375mg/m 2 intravenous infusion from the first day to the tenth day. 38 patients(control group)received chemotherapy regimen of CF 200mg/m 2 and 5-Fu 375mg/m 2 intravenous infusion from the first day to the tenth day. ALL patients underwent two cycles of the therapy at least. Results The efficacy of the treatment group and control group was 39 5% and 18 4% respectively, which had a significant difference. The hematologic toxicities in the treatment group, especially leukopenia and anemia, were significantly than those in the control group less. Conlusion The results indicated that sodium cantharidate combined with 5-FU and CF treatment of colorectal cancer had moderate activity and less toxicity, further clinical investigation of which should be performed.
出处
《中国医药导刊》
2004年第1期70-70,共1页
Chinese Journal of Medicinal Guide
关键词
ALERT
肾移植
氟伐他汀
降脂治疗
安全性
Advanced colorectal cancer
Sodium cantharidate
CF
5-FU
Combination chemotherapy
