摘要
自甘草(Glycyrrhiza uralensis Fiseh)的干燥叶中分离到7个甙类成分,经化学方法和光谱分析确定结构为原儿茶酸-1-O-β-D-呋喃木糖酯甙(1-O-protocatechuyl-β-D-xylopyranose,Ⅰ)、洋芹素-6,8-C-二葡萄糖甙(vicenin-2,Ⅱ)、异鼠李素-3-O-芸香糖甙(narcissin,Ⅲ)、山柰酚-3-O-芸香糖甙(nicotiflorin,Ⅳ)、山柰酚-3-O-β-D-葡萄糖甙(astragalin,Ⅴ)、槲皮素-3-O-芸香糖甙(rutin,Ⅵ)和槲皮素-3-O-β-D-葡萄糖甙(isoquercitrin,Ⅶ)。其中,Ⅰ是新化合物,命名为乌拉尔新甙(uralenneoside);Ⅲ在本属植物中为首次报道;Ⅲ～Ⅶ在乌拉尔甘草中首次分得。Ⅱ～Ⅶ都是已知活性成分。
Seven glycosidic constituents have been isolated from the dried leaves ofGlycyrrhiza uralensis Ficsh. (Leguminosae). The Structures of these compounds havefor identified as 1-O-protocatechuyl-β-D-xylose (Ⅰ), apigenin-6, 8-di-C-β-D-glucopyranoside (vicenin-2, Ⅱ), isorhamnetin-3-O-rutinoside (narcissin,Ⅲ) kaempferol-3-O-rutinoside (nicotiflorin Ⅳ), kaempferol-3-O-β-D-glucopyranoside (astragalin, Ⅴ), quercetin-3-O-rutinoside (rutin, Ⅵ), and quercetin-3-O-β-D-glucopyranoside (isoquercitrin, Ⅶ) by chemical method and spectroscopicanalysis. Among these compounds, Ⅰis a new compound, named uralenneoside; Ⅲwas reported for the first time in the genus; Ⅲ to Ⅶ were isolated for the first time fromthe species. Ⅱ to Ⅶ are known biologically active constituents.
出处
《药学学报》
CAS
CSCD
北大核心
1992年第6期441-444,共4页
Acta Pharmaceutica Sinica
关键词
乌拉尔甘草
黄酮碳键甙
Glycyrrhiza uralensis Fisch
1--O--Protocatechuy1--β--D--xylose
Flavone--C--glycoside
Flavonol--3--O--glycoside
